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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

维多利亚的秘密内衣秀刚刚拉开华丽巨幕,今年的秀也是有史以来最奢华复杂的一次。
headway

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

n. 保守派(党),
v. 扛,肩负,承担,(用肩

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Although it looked like the mobile patent wars might cool off after several settlements late in 2014, this year kicked off with a skirmish between Apple and Ericsson over patent royalties related to wireless communications. BlackBerry used to be pretty litigious: It even took on celebrity Ryan Seacrest over its keyboard! But these days it is more focused on trying to convince smartphone buyers that its technology is cool again. Or at least relevant.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Moreover, a “turnaround in the short run is unlikely”, given China’s efforts to rebalance its economy from exports towards consumption (thereby reducing demand for imports of intermediate inputs), reinforced by “government policy to stimulate the use of domestic suppliers” and rising protectionism elsewhere, he argues.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 11月300城市土地市场量跌价涨
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

那么多的人视而不见,不承认事实。真相是泡沫无处不在,随时准备爆掉。证据越来越多,结论只有显而易见的一个:泡沫破灭的风险最高可达98%。2014年这次崩盘几乎是铁定要发生的,躲过这枚子弹的概率只有区区2%。
The other issue with tanking is Philly, Phoenix, and Brooklyn are all bad teams. It's going to be hard to outflank those outfits.
Job history
3.9 全面加强政府自身建设

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Major pharmaceutical companies, working with the American Cancer Society, will steeply discount cancer drugs for patients in African countries. Cancer kills 450,000 people across the continent each year, but many types here are among the most treatable: breast, cervical and prostate tumors.
Busting through the glass ceiling
目前还不清楚绑架者的身份以及他们的目的。
After all, during the last round of collections, the most striking pieces — from Louis Vuitton, Dior, Proenza Schouler, Narciso Rodriguez — had a streamlined momentum that wasn’t dragged down by any decade-related reference, or identity. They were clothes that went striding into the future, freed from the weight of the past.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

According to the Hurun Report’s annual China Rich List, Yao Zhenhua’s net worth surged more than nine times to $17.2bn last year, making him the country’s fourth richest person. Last year he was ranked 204th.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Brazil's President Dilma Rousseff, who is facing impeachment, slashed her own salary by 10% to $103,400 a year last October as part of a wider austerity drive.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

A lack of capital and experience is the biggest obstacle for college entrepreneurs, the report suggested, stating that 40 percent of such young entrepreneurs rely on external capital such as loans from banks, investment organizations, schools and the government.
金融和房地产是国产品牌的支柱,榜单中有38个金融企业,23个房地产企业,占了榜单品牌的30%。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

大学生创业的常见领域包括餐饮、农业、信息技术、运输、教育、文化。报告称,13.8%的创业者对住宿、餐饮业感兴趣,13.7%的创业者选择农业。
说到底,我预期这些新的领导人将开始从更广泛的候选人中选拔人员,并把不同背景的人任命为自己的直接下属,从而驳斥那些根据当前的失衡来外推还需数十年才能实现领导层男女平衡的悲观者。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

A New Year greeting to cheer you from your daughters.愿女儿的新年祝福带给你快乐。
因此,看看吧。我真诚地希望你们会喜欢它们,就像我在挑选和编辑它们时那样。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

王斌表示,去年母婴传播率也达到了历史最低点,从2012年的7.1%下降到2017年的4.9%。
2. Smart water bottle
2.The Fresh Prince of Bel Air was Almost Bankrupt
6. 米兰达?可儿

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

They come mostly from 50 different industries including food and beverage, automobiles and auto components, media, retail, energy and the Internet.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

HSBC economist Hongbin Qu said the survey pointed to lost momentum in China's manufacturing sector: He expects Beijing to respond with measures to counteract the slowdown.
3. Your boss received your résumé from a contact of a contact。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

2.“老爹身材”受热捧

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

不过,黄金比萨早就不是第一种加入了黄金的食物。“马尼拉社交俱乐部”是纽约威廉斯堡一家菲律宾餐厅,今年早些时候,餐厅老板Bj?rn DelaCruz制作了一款昂贵的黄金水晶宇部甜甜圈。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

但是这并没有阻止科学家在实验室发展人造大脑。今年奥地利的科学家仅从干细胞开始,成功地创造出等同于9个周大的婴儿的大脑。目前,这些大脑只有豌豆大小,也不能思考。阻止这些试验品发育成具有完全功能的大脑的因素是它们没有血液供给。
Strong in many categories, but without quite managing to be a front runner in any. Perhaps Timothee Chalamet's performance is its best chance of awards success.
Tesla:In an effort to blunt criticism about slow refueling times for battery-powered cars, Tesla TSLA -1.54% starts to roll out of a network of battery-swap stations. CEO Elon Musk must hope he can outdo Shai Agassi’s Better Place, which tried to build a whole company around battery-swaps before going bankrupt in 2013.
*Writing for a Variety Series: “Last Week Tonight With John Oliver”

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 国开行棚改项目审批权回收总行
Review Article

Influenza neuraminidase: A druggable target for natural products

我的预感是到了3月份,今年的应考新秀们就会看起来很棒,并且会远比去年要好,去年是近几年来最不被看好的一年。新奥尔良和华盛顿都需要一个明确的方向,并且他们不久就会做出各自的选择。
专家警告说,在普通词汇中添加数字或符号根本没用。斯莱恩说:“黑客们都知道你的小伎俩,对容易破解的密码稍作调整不会更安全。”
Remedy: The tricky aspect of this regret is that it’s typically rooted in hindsight. Only after you’ve left the job and have moved on to something better, do you start beating yourself up for not making the leap sooner, even if it hadn’t been practical or possible. What you can do is to identify the factors that kept you in your former position as red flags to be aware of in the future and work to line up supports that will allow you to more quickly capitalize on other opportunities as they may present themselves. This could include reviewing and updating your resume with new accomplishments on a monthly or quarterly basis, keeping your LinkedIn account current, building up a contingency fund to allow you to feel less tethered to your current pay check and staying in the loop on industry news and gossip to be aware of where your skills and experience could be of value.
The quality of consumer goods imported through channels other than e-commerce proved to be higher, with only 29 percent falling short of standards, according to figures released by the administration.
adj. 仁慈的,(为)慈善事业的,宽恕的

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

立场:呼吁结束政府停摆局面
But at the end of a madcap Golden Globes (Ms. Fey toasted it as 'the beautiful mess we hoped it would be'), the major honors soberly ended up with the favorites. David O. Russell's con-artist caper 'American Hustle' led with three awards, including best film comedy. And despite missing out in the other six categories it was nominated in, the unflinching historical drama '12 Years a Slave' concluded the night as best film drama.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

It was visible in practically every brand that edged from the 1960s to 1970s for the season currently in stores, including Alberta Ferretti, Pucci and Etro.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

It was a rare glimpse into his closely guarded personal life that also put at risk Apple’s brand in less tolerant parts of the world. Mr Cook was driven to take a stand by his experiences growing up in Alabama, where he has talked of seeing discrimination that “literally would make me sick”.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

平板电脑的病毒出现。
“If lenders are too optimistic during market booms and too pessimistic in downturns, that could be a good reason for authorities to set conservative capital requirements,” he suggests. “Higher haircuts might dampen the initial run-ups, but they could also dampen the subsequent fallouts when tides turn.”
9. 2012年搞笑诺贝尔奖之解剖学奖
Local champions

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

报告指出,他们的家庭平均每月大约会收到200美元,这占到了他们家庭收入的60%。使用这笔稳定的汇款,他们的家人可以解决吃饭、住房、上学、医疗问题,改善卫生条件,进行一些投资,或者有一定的存款。
“If hearing that the CEO of Apple is gay can help someone struggling to come to terms with who he or she is, or bring comfort to anyone who feels alone, or inspire people to insist on their equality, then it’s worth the trade-off with my own privacy,” he wrote in Bloomberg Businessweek in October.
director
If Dwyane Wade lost 30 pounds of muscle, you wouldn't be able to tell him apart from the high school version of himself.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

上月,在全国70个大中城市中,新建商品住宅价格环比上涨的有55个,价格持平的有4个,价格下跌的有11个。环比下跌的城市包括深圳(下跌0.3%)、杭州(下跌0.4%)和厦门(下跌0.2%)。
一种全新的器官被归类了。研究人员同意为肠系膜归类,这种器官显然一直隐藏在我们的消化系统中。但这只是其中的一方面,因为我们还不确定它到底是什么。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

限制措施开始见到成效。中国商务部周四表示,1月份中国企业对外非金融类直接投资金额同比下降了36%,至530亿元人民币(合78亿美元)。去年12月的同比降幅为39%。
Judge for yourself.
9.Use One Planner
愿你一切称心如意,快乐无比。
每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

We will maintain ethical conduct and moral integrity at all times.
For once, the Lakers are in good spot and don't have to rush into anything. Take some time. See what they have. They're not making the playoffs with that defense, but that's not really the point of this season anyway.
2011年在达洛伊西奥15岁时,他就曾获得来自李嘉诚的种子投资。一年之后Summy发布,并在短短一个月内吸引了500,000名用户,在28个国家登上了新款应用软件热度榜的首位。对于一个连高中都还没毕业的人来说,雅虎的收购可谓意义深远。不过,达洛伊西奥的过人之处可不只是技术知识丰富这一点。在他连胡子都不用刮的时候,他就强烈向往、渴望著有朝一日能在科技领域做出一番大的成就。不仅要创新,还要有所成就,当然,还要大把赚钱。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Payouts also varied substantially between industries and cities. The average bonus at financial institutions was over Rmb17,200, while those in the education sector got less than half of that on average at less than Rmb7,500.
安娜的工资也就是巴西的最低月薪,仅330美元。因此门票对普通老百姓来说实在过于昂贵。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 门禁卡不能成安全“地雷”
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

课程安排:每隔一个周末在芝加哥上课,共计大约18门课程,包括4门选修课。学员在芝加哥住校学习3周,在香港和伦敦分别学习1周。
May the beauty and joy of New Year remain with you throughout the new year!愿新春美景与欢乐常伴随你!
在007电影主题曲榜单上,《女王密使》的主题曲获得荣誉推荐。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

“‘降温’措施(是)影响香港(住宅)地产市场的最重要问题,”莱坊估价主管林浩文(Thomas Lam)说,“这正是过去两三年里所有大型机构的方案都在关注写字楼市场的原因。”
我们错了——最终睾丸还是与免疫系统有关联的。研究人员发现了“一扇非常小的门”使睾丸可以向免疫系统发送单向信号,这解释了为什么一些男性会被不孕症所困扰,也解释了某些癌症疫苗一直失败的原因。
Finding Dory releases on June 17, 2016.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

4. Fruit Mold

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

节目21 歌曲《幸福》,毛阿敏

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

然而,北方高等商学院毕业生的国际化流动程度最高,2014届毕业生有85%曾在国外工作。
Attractions: Festivities for the 2014 World Cup

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

首先,正如咨询与培训机构RedPrairie公司的供应链专家汤姆?科赞斯基所言,一提到物流行业,多数人都觉得它“没有吸引力”,是一项乏味且薪水不高的仓储工作。
总的来说,在选择就读EMBA的原因中,创业排在最末(10分中得5.5分)。学员的主要动机是学习管理(9.1分)、拓宽人脉(8.3分)及增加收入(8.1分)。
11月中国外汇储备下降872.23亿美元,接近8月下降940亿美元的纪录——该月中国央行出乎全球市场意料地允许人民币在三天里贬值4.6%。
Variety Talk Series: “Last Week Tonight With John Oliver” (HBO)

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

[.di:m?'gr?fik]
28 September

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 构筑“一带一路”建设重要支撑区
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

克里斯汀“伯德小姐”是一名高中生,她“家里贫困拮据”,但却向往冒险成熟的生活,憧憬机遇的来临。但在她所就读的萨克拉门托天主教学院她却什么也寻求不到。影片讲述了主角高三一年的经历,包括她第一次恋爱,她在学校参加舞台表演,以及最重要的,她申请大学的故事。
Payne, a former lottery pick, missed time with a foot injury and hasn't shown any major progress as a shooter or a defender in year two.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

The only things in the way are his staff, Republicans in Congress and the limits of his power. And those are important. Campaign promises of 45 per cent tariffs on Chinese goods have turned into investigations into Beijing’s intellectual property regime.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Celebrity Latin tattoos may be fuelling a revival of the ancient language in schools, it emerged today。  明星们的拉丁语纹身引发了一阵学习拉丁语的热潮。
Ellen DeGeneres
据预测,在大宗商品价格上涨和需求温和上升的推动下,2017年以美元计的新兴市场国家出口额将出现自2014年以来的首次增长。
唉。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

[.?ndi'nai?bl]
Keep around people who like to remind you how smart you are, and stay even though they think you are a dick.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

人事工作类
英国剑桥大学Judge商学院(Judge Business School)排名上升速度最快,今年上升19位,名列第29位,这得益于其在高管MBA排名中的出色表现(该学院今年首次参与此项排名)。华威商学院(Warwick Business School)重返榜单前20名(位列第19),该校去年未参加管理硕士排名。
I once had an advisor that said to me when I expressed fear of a difficult class, "Do you want to get an education or not?"

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

我们曾经都经历过:老板们和经理们让我们的生活越来越糟糕,不能管理好一堆文件,不理整个团队的员工。我之前写过一篇文章“不明智老板的特点”,在那篇文章里,一位考虑周到的评论者列出了他对如何做一个明智的老板的一些点评。
我是否有从一天当中能抽出时间来给自己?我们都需要一点“自我时间”。每天留出一些时间放松一下,做你喜欢做的事情——阅读、冥想、看电视、烹饪、跟你爱的人共享黄金时光等等。
Security questions risks

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

“尽管我本质上是一名工程师和分析人员,但迄今为止我所做过的最重要的决定都与此无关,它们永远是基于直觉,”他去年在曾就读MBA的杜克大学(Duke University)对一名采访者表示。
Once Upon A Time

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

据斯派克回忆,一天,拍摄工作结束后,另一位编剧詹妮弗·克里滕登在走廊叫住他,问:"你一定要这样吗?你确定这样不会毁了朱莉娅的前程吗?"考虑到当年朱莉娅凭此剧获得艾美奖,我们不妨说这场舞戏其实让这位女演员在演艺事业上更进了一步。为了怀旧,您不妨抽空再去回顾一下伊莱恩和她著名的"伊莱恩舞步"。
出口的提振在很大程度上源自对美出口,其价值自3月份以来首次出现同比增长,同比增6.9%,至368亿美元。在其他出口目的地中,对欧盟出口同比增长5.1%,至299亿美元,对日本出口同比增长3.2%,至122亿美元。
Restaurants and other retailers across the United States are offering free or discounted items and service to the nation's military veterans Wednesday in honor of the annual Veterans Day holiday observance.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

莱蒂齐娅·巴塔利亚(Letizia Battaglia)
Kristen Stewart definitely did some 'butt' kicking at the Nickelodeon Kids' Choice Awards 2013 on Saturday. The star strutted down the purple carpet in a dazzlingly deep blue and black top and tiny shorts that had a miniscule checkerboard pattern. Kristen was nominated for two awards at the live show - Favorite Movie Actress for The Twilight Saga: Breaking Dawn - Part 2 and Favorite Female Buttkicker for Snow White and the Huntsman.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

[in'fekn]
Among French schools, Toulouse Business School made the best progress, up 14 places, after featuring in the Executive MBA ranking for the first time.
2.室内类比赛项目

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

研究人员表示,去年之所以特别引人瞩目,是因为除了1月和4月以外,每个月都会创下新的全球高温记录,或与记录持平。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

201001/93725.shtmlNews trumpedcelebrities in 2010 as the BP oil spill in the Gulf of Mexico and World Cup soccer in South Africa topped the list of most-searched items of 2010, according to Yahoo!
Brazil's President Dilma Rousseff, who is facing impeachment, slashed her own salary by 10% to $103,400 a year last October as part of a wider austerity drive.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Chazelle’s musical was the hot favourite going into the evening, with a record-tying 14 nominations. Chazelle won the best director award, while Emma Stone won best actress for her performance in the film, which was produced by Lionsgate. There were other La La Land Oscars for score and best original song.
当然,这得取决于苹果是否能设法用更便宜的零部件、更慢的处理器、分辨率更低的屏幕、以及也许是塑料机身来造出一部330美元的iPhone。而用蒂姆?库克上周在高盛公司(Goldman Sachs)一次会议上的话说,它决不能是个“低劣产品”。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Bank of China followed the trend, with profits up only 1.3 per cent and ROAA declining by 0.1 percentage points.
……带着狗来面试。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

13个原因
STONINGTON, CONN.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

时间:2011-12-28 编辑:Richard

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

China Poised to Claim Half of Global Online Game Market, Report Says
FRESH OFF THE BOAT (ABC, Feb. 4) A Chinese-American family adjusts to life in mid-'90s Florida in this culture-clash comedy based on a memoir by the restaurateur and food-and-travel-show host Eddie Huang. Hudson Yang plays the 11-year-old hip-hop wannabe Eddie, and Randall Park (Kim Jong-un in “The Interview”) plays his father, proud proprietor of a suburban steakhouse.
But most overseas islands are sold as freehold properties.
国家已出台多项措施来推动新能源汽车,包括免税、发放购车补贴,以及要求政府部门购买更多的新能源汽车。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 建陶业盼借政策东风健康发展
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

然而,相关数据似乎表明,中国企业投资西方经济体的步伐可能在放缓。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 家具行业的新商业模式悄然崛起
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

在2014年开始的这轮放缓之前,中国的雇主对于奖金没有这么吝啬。奖金的数额会大大高于一个月的薪水,让回家度假的员工能拥有足以为长辈和其他家庭成员购买礼物(或存为积蓄)的现金。
All but one of the other top 10 categories reflected public fascination with celebrities. Teen pop sensation Miley Cyrus was in third place in the search rankings and television personality Kim Kardashianwas not far behind at fourth place. They were followed by Lady Gaga at No. 5, actress Megan Fox in seventh place, with Justin Bieber, American Idol and Britney Spears completing the top 10. The iPhone stood out as the exception, coming in sixth.
从一个孩子的视角,讲述佛罗里达州一家汽车旅馆社区的生活。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Classic cars:Prices plummet as an enormous supply of post-war classics, hidden away on an off-shore island, becomes available for the first time in 50 years. Collectors are especially eager to find Packards, Studebakers, Hudsons, Nashes, Kaisers, and Henry J’s. More’s the surprise because all of the cars are in running condition and are used as daily drivers.
Enrollment: NA

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Mark Williams, chief Asia economist at Capital Economics, adds: “We expect that the performance of EM exports will continue to improve in 2017, with export values rising modestly in year-on-year terms.”
他通过电梯门递出一张纸条,上面写着"有人被困在电梯内,请叫物业来帮忙。"寄希望于有人可以捡到并来救他。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

排球拳击乒乓球举重沙滩排球铁人三项艺术体操蹦床篮球射击羽毛球艺术体操足球网球

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

It was the age of wisdom, it was the age of foolishness…
4. 马克·特纳四重奏(Mark Turner Quartet),《天堂里的车床》(Lathe of Heaven), ECM。这是次中音萨克斯手马克·特纳13年来第一次以领队身份推出专辑,他喜欢同小号手阿维沙伊·科恩(Avishai Cohen)奏出流畅的互动,在后波普规范中发现全新意义。他的作曲中有纯粹的神秘,由乔伊·马丁(Joe Martin)担任贝斯手,马库斯·基尔默(Marcus Gilmore)担任鼓手的节奏组亦是一丝不苟。
尽管中国的私人财富大幅增长,但中国的亿万富豪仍未跻身全球顶级富豪行列。胡润估计,中国首富、万达集团(Wanda Group)掌门人王健林在全球富豪中排名第26位。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 热点城市新房价格上月没涨
Paper

Length-scale dependence of protein hydration-shell density

[slu:]
但是即使在一些糟糕的经济环境下,一些岗位并不是值得一做的。当你在决定是否要放弃的时候,你是不是应该寻找一些迹象呢?这里有10种信号告诉你是否该找一份新的工作呢:
Meanwhile, celebrated American rapper Eminem proved to be the comeback king as he picked up the Best Hip Hop gong. The Lose Yourself hitmaker was up against the newer faces of hip hop, including Drake, Future, Kendrick Lamar and Post Malone.
engaged

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 前2月一线土地出让增84%
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

作为宝莱坞片酬最高的女演员之一,迪皮卡·帕度柯妮是2015全球十大美女榜的季军。在印度,她是性感女神、时尚偶像。帕度柯妮在印度各类魅力女性榜上的排名都很靠前。完美的身材、深邃的眼神和迷人的微笑使她脱颖而出。她是许多品牌的代言人,包括天梭、索尼数码相机、雀巢咖啡、沃格眼镜、美宝莲和百事可乐等等。
自从1995年游戏第一次面世以来,续集和新版本在之后也接踵而来。但是,对于许多仙剑迷来说,《仙剑1》激动人心又充满悲伤的故事情节是其他任何版本也代替不了的。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

一位伦敦软件神童的“硅谷梦”成真,雅虎(Yahoo)斥资近3000万美元收购了他制作的新闻应用。
Leading actress Sun Li played Zhou in the drama. Despite her age, Sun, who was born in 1982, still successfully presented a lovely and innocent teenage Zhou in the eyes of many audience members.
你有D型人格特征吗?有测试表明,拥有这种鲜为人知的性格的人非常善于隐藏情感,甚至他们自己都没有意识到自己很孤单、很焦虑。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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我祖母最喜欢的一首诗是威廉o埃内斯特o亨利的《不可征服》(Invictus)。我父亲把这首诗挂在厨房墙壁上,所以在成长过程中,我每天都会读到它:“我,是我命运的主宰。我,是我灵魂的统帅。”我能为每个人,特别是初入职场者提供的最好建议,就是欣然接受你作为命运主宰的角色。当机会出现时,抓住机会并敢于说“Yes!”
Italy, one of the eurozone’s weaker economies, received the most investment of any EU nation from Chinese companies. That was largely down to a $7.9bn deal between Pirelli and ChemChina. France was the number two country, receiving $3.6bn of investment through a string of big deals in the tourism and infrastructure sectors.

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